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Synthetic cannabinoids are so-called because their effects do, to a certain degree, mimic those of marijuana. This is because both marijuana and synthetic weed bind to the CB1 and CB2 cannabinoid receptors in the brain, which control such functions as short term memory and appetite. However, synthetic cannabinoids seem to have a much greater affinity for the CB1 receptors which accounts for its strong psychotropic properties. Some research has also shown that JWH-018, the most commonly used of these synthetic cannabinoids due to its apparent similarities to cannabis, is also far more potent than cannabis.

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